Basement membrane and basal lamina difference

Difference Between Basal Lamina Vs Basement Membrane - The

What is the difference between the basal membrane and the

Basal membrane is basically two basal lamina's fused together. It is found beneath every epithelium and can be seen by optical microscope (whereas basal lamina can't). Basal lamina of one tissue+basal lamina of another tissue. I've never heard of basement membrane (but english is not my first language, so I guess that explains that) Many cells, including skeletal muscle fibers, are coated by a layer of extracellular matrix material called the basement membrane (BM). 1 The BM, in turn, is composed of two layers: an internal, felt-like basal lamina (BL) directly linked to the plasma membrane, and an external, fibrillar reticular lamina. BMs contain protein and carbohydrate but no lipid or nucleic acid The basal lamina is a layer of extracellular matrix secreted by the epithelial cells, on which the epithelium sits. It is often incorrectly referred to as the basement membrane, though it does constitute a portion of the basement membrane.The basal lamina is visible only with the electron microscope, where it appears as an electron-dense layer that is 20-100 nm thick (with some exceptions. Structure. As seen with the electron microscope, the basement membrane is composed of two layers, the basal lamina and the reticular lamina. The underlying connective tissue attaches to the basal lamina with collagen VII anchoring fibrils and fibrillin microfibrils.. The basal lamina layer can further be divided into two layers

1. basal lamina which is the upper part of basement membrane and is attached to the epithelium. consisting of protein filamens. 2. reticular lamina which is the lower part of basement membrane and is attached to the underlying connective tissue ( lamina propria ) , consisting of reticular fibers Difference bwteen basal lamina and basement membrane Ask for details ; Follow Report by Saksham703 24.03.2018 Log in to add a commen Basement membrane and external lamina have similar structures. Basement membranes have five major components: type IV collagen ( Fig. 4.11 ), laminin, heparan sulfate, entactin and fibronectin. With the exception of fibronectin, these are synthesized by the parenchymal cells The difference between a basal lamina and a basement membrane is that A) the basal lamina is thicker. B) they lie on opposite surfaces of the epithelium. C) a basal lamina plus a layer of reticular fibers equals a basement membrane. D) only the basal lamina can be seen by light microscopy

Difference between basal lamina and basement membrane

Basement membrane is a thin extracellular layer that commonly consists of two layers, the basal lamina (lamina densa) and reticular lamina. The basal lamina (lamina = thin layer, about 30-70 nanometers in thickness) is closer to—and secreted by—the epithelial cells The brown coloured basal lamina. Draw and annotate: A few kidney tubules with surrounding basal lamina. Reflection: How does the basal lamina appear? Why are the nuclei of the epithelial cells not visible but the basal lamina can be seen? What is the difference between the basal lamina and basement membrane basal lamina vs reticular lamina Results Test Prep , Inc. Glomerular Basement Membrane (GBM) - Anatomy Parte 1/5 - Generalidades do Tecido; Lâmina e Membrana Basal - Duration: 43. The basal lamina, a mixture of glycoproteins and collagen, provides an attachment site for the epithelium, separating it from underlying connective tissue. The basal lamina attaches to a reticular lamina , which is secreted by the underlying connective tissue, forming a basement membrane that helps hold it all together Some authors use the term basal lamina to include the lamina lucida and lamina densa (Gartner and Hiatt, 2007), while others use basal lamina to denote the lamina densa (Young et al., 2014). The terms basement membrane and basal lamina are often used indiscriminately in the literature and standard textbooks, which may cause confusion

What is the difference between basal lamina and basement

Basement Membrane is composed of... Basal Lamina/Reticular Lamina It prevents paracellular exchange of materials and maintains concentration difference between environments on either side of the An outer membrane plaque linking the hemidesmosomes to the basal lamina by anchoring filaments (laminin and integrin) Mistaken for. (ii) Lamina fibrosa o reticular: Es una capa gruesa interna, compuesta de colágeno o fibras reticulares del tejido conectivo subyacente. Es visible con microscopio óptico. La membrana basal proporciona soporte elástico. También permite el intercambio químico selectivo entre los tejidos epiteliales y los vasos sanguíneos circundantes Download Citation | On May 1, 2003, Joshua R Sanes published The Basement Membrane/Basal Lamina of Skeletal Muscle | Find, read and cite all the research you need on ResearchGat Basement membrane definition is - a thin membranous layer of connective tissue that separates a layer of epithelial cells from the underlying lamina propia Basement membrane (BM) can be formed by the fusion of either two adjacent basal laminae or a basal lamina with an adjacent reticular lamina of connective tissue. BM, composed mainly of TYPE IV COLLAGEN ; glycoprotein LAMININ ; and PROTEOGLYCAN , provides barriers as well as channels between interacting cell layers

The Basement Membrane/Basal Lamina of Skeletal Muscl

Basal lamina - Wikipedi

I am going to use the basement membrane only when I talk about epithelia. There is often confusion between the term basement membrane and the term basal lamina. Basement membrane really refers to the structure you see with the light microscope. Basal lamina is part of the structure you see using the electron microscope File:Basal lamina.jpg. The basal lamina is a layer of extracellular matrix on which epithelium sits and which is secreted by the epithelial cells. It is often confused with the basement membrane, and sometimes used inconsistently in the literature, see below.. It is typically about 40-50 nanometres thick (with exceptions such as the basal laminae that compose the 100-200 nanometre thick. basallamina, basal lamina, Lamina basalis. The basement membrane (Terminologia histologica: Membrana basalis) is a homogenous layer of the extracellular space located closely beneath basal epithelial cells or membranes of some special types of cells (see below). The name basement membrane derives from light microscopic appearance The basement membrane anchors the epithelium to connective tissue and creates a diffusion barrier. The basement membrane is composed of a band-like layer of fibers and large proteins and is tightly bound to the cytoskeleton of cells. The basal lamina and lamina reticularis form the basement membrane

Basement membrane - Wikipedi

  1. a and then splay out laterally. They are more readily seen in sections taken parallel to the basal la
  2. antly in a basal-to-apical direction, accumulating in the airway lumen, as evidenced by their presence in bronchoalveolar lavage fluid. 1-3 In contrast, intraepithelial T lymphocytes and dendritic antigen-presenting cells (APCs) cross the epithelial basement membrane in both basal-to-apical and.
  3. Basement membranes attach layers of tissues in the body. Learn how the basement membrane helps our skin counteract the effects of gravity and explore its various other functions in this lesson
  4. a, associated proteoglycans, and other as yet incompletely defined components. the number of times these processes penetrated the type II cell basement-membrane la
  5. a is a layer of extracellular matrix on which epithelium sits and which is secreted by the epithelial cells. It is typically about 40-50 nanometers thick (with exceptions such as the basal la
  6. a is a layer of extracellular matrix secreted by the epithelial cells, on which the epithelium sits. It is often confused with the basement membrane, and sometimes used inconsistently in the literature, see below.. It is typically about 40-50 nanometers thick (with exceptions such as the basal la
The difference between a basal lamina and a basement

The epidermis functions in skin as first defense line or barrier against environmental impacts, resting on extracellular matrix (ECM) of the dermis underneath. Both compartments are connected by the basement membrane (BM), composed of a set of distinct glycoproteins and proteoglycans. Herein we are reviewing molecular aspects of BM structure, composition, and function regarding not only (i. Basement membrane structure and function - عبد الله رضا MD عبد الله رضا , M.D. Loading... Unsubscribe from عبد الله رضا , M.D.? Cancel Unsubscribe. Working.

All epithelia rest on a basement membrane, which consists of two components, the basal lamina, secreted by epithelial cells, and a reticular lamina, secreted by fibroblasts in the underlying connective tissue. The basal lamina is, in turn, subdivided into lamina lucida and lamina densa. Serosa 15,000 • Lamina Reticularis attached to basal lamina with anchoring fibrils (type VII collagen fibers) and microfibrils (fibrilin) is collectively known as the basement membrane. 22. • Basal lamina consists of a fibrilar layer called lamina densa which is separated from the plasma membrane of the adjacent cell by a narrow electron-lucent zone, lamina lucida Define basal lamina. basal lamina synonyms, basal lamina pronunciation, basal lamina translation, English dictionary definition of basal lamina. n. basement membrane. n. A thin noncellular layer located between epithelial cells and the connective tissue that underlies them,.

Polarity: basal vs apical (luminal); lateral; specialized plasmalemma, appendages and junctional complexes. glycocalyx (apical) vs basement membrane (bm: basal lamina secreted by epithelium + lamina reticularis secreted by connective tissue The main difference between fibronectin and laminin is that the fibronectin is a glycoprotein found in the extracellular matrix (ECM) and in the blood plasma whereas laminin is a glycoprotein, which serves as the main component of the basal lamina.Furthermore, fibronectin is essential in wound healing while laminin is vital in the neural development and peripheral nerve repair Basal Lamina is an extracellular structure that is closely related to the plasma membrane on the epithelial and endothelial cell bases and surrounds muscle and adipose tissue. Basal Lamina is a composite extracellular structure located on the basal surface of epithelial cells and the membranous structure of connective tissue lamina [lam´ĭ-nah] (L.) 1. a thin, flat plate or stratum of a composite structure; called also layer. 2. vertebral lamina. basal lamina (lamina basa´lis) the layer of the basement membrane lying next to the basal surface of the adjoining cell layer composed of an electron-dense lamina densa and an electron-lucent lamina lucida. lamina basila´ris the. A basal layer, or stratum basale, is the deepest of the three layers. The basal layer is a single layer of cuboidal epithelial cells overlying the basement membrane, which, in turn, is situated superior to the lamina propria. The basal layer produces the basal lamina of the basement membrane

Math_Activity_Dickey - Scientific Notation and Unit

basal lamina: [ lam´ĭ-nah ] ( L. ) 1. a thin, flat plate or stratum of a composite structure; called also layer . 2. vertebral lamina . basal lamina ( lamina basa´lis ) the layer of the basement membrane lying next to the basal surface of the adjoining cell layer composed of an electron-dense lamina densa and an electron-lucent lamina lucida .. The terms apical cell and basal cell are used to describe the relative locations within stratified epithelium. The most common one is stratified squamous, found on the surface of your skin and lining the vagina, mouth, esophagus and anus. Here onl.. Laminin 2 - basement membrane protein that links integrin (or dystroglycan) to ECM components. Lamin A is a nuclear envelope protein that forms filaments. Lamina is the basement membrane as seen by electron microscopy, the basal lamina The Holy Spirit Gives Life to all Living Cells -- Bacteria, Plant and Animal The basal lamina is a layer of extracellular matrix on which epithelium sits and which is secreted by the epithelial cells. It is often confused with the basement membrane, and sometimes used inconsistently in the literature, see below.. It is typically about 40-50 nanometres thick (with exceptions such as the basal laminae that compose the 100-200 nanometre thick glomerular basement membrane)

what's basement membrane and lamina propria? what is their

  1. a + reticular la
  2. The genes COL4A5 and COL4A6, coding for basement membrane collagen chains alpha 5(IV) and alpha 6(IV), are located head-to-head in close proximity on human chromosome Xq22 and COL4A6 is transcribed from two alternative promoters
  3. a or basement membrane that separates epithelial cells from the underlying tissue. Epithelia cells are polarized with an apical surface that faces the lumen of a tube or the external environment and a basal surface that attaches to the basement membrane
  4. a Draw And Annotate: A Few Kidney Tubules With Surrounding Basal La
  5. a and when this la..

Difference bwteen basal lamina and basement membrane

  1. in is that fibronectin is a glycoprotein that exists mainly in the extracellular matrix and blood plasma while la
  2. a offers la
  3. Stratum Spinosum Basement Membrane Zone. The keratinocytes of the stra-tum basale are associated with the dermis via the basement membrane zone.The basement membrane zone contains elements of both the epidermis and dermis. In addition to providing structural support to the skin, the basement membrane zone is the filter through which nutrients pass from the dermal blood vessels to the basal.
  4. a, is a sheet of proteins and other substances to which epithelial cells adhere and that forms a barrier between tissues. Once tumours are able to break through this membrane, cancerous cells not only invade surrounding tissue substances.
  5. a). The basement membrane provides structural and metabolic support to epithelia. It is usually 30 - 60 nm thick and made up of a feltwork composed of collagenous and non-collagenous glycoproteins and proteoglycans
  6. a and reticular la
  7. a vs Basement Membrane. Hello everybody can someone tell me what's the difference between Basal la

Basement Membrane - an overview ScienceDirect Topic

The lamina densa, whose collagen IV fibers are coated with the heparan sulfate-rich proteoglycan perlecan, and the lamina lucida (made up of laminin, integrins, entactins, and dystroglycans) together make up the basal lamina. Integrins are not part of the basal lamina, they are part of desmosomes which are in the basement membrane but not the. It is made up of two district layers, the basal lamina and the reticular lamina which are joined together by collagen fibers. What is the function of this membrane? Read this article to discover more. What is the function of the basement membrane? The basement membrane has a number of important functions

Basement membrane zone, Skin structure. Helping patients make the most of their treatment; Illness Managment : Psoriasi Read Differences in the width of the intercellular spaces in the epithelial basal infolding and the renal glomerular filtration site between freeze‐substitution and conventional fixation, Journal of Anatomy on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips Approx. x 25 000. Tumour basement membrane measurement log Figure 2. This figure shows four examples of the basal region of colorectal epithelial neoplasms and the adjacent basement membrane area and stroma. Immediately adjacent to the cell membrane can be seen the lamina deiisa of the basement membrane. In a, it is nearly normal throughout There are four main types of cell-cell junctions: Three are different types of connecting junctions, that bind the cells together. occluding junctions (zonula occludens or tight junctions) ; adhering junctions (zonula adherens).; desmosomes (macula adherens). There are also 'hemidesmosomes' that lie on the basal membrane, to help stick the cells to the underlying basal lamina Basal membrane or Basal lamina is not the same as Basement membrane. 2. Rather , Basal lamina or Basal membrane is a part of the Basement membrane. EXPLANATION : Often the basement membr view the full answer. Previous question Next question Get more help from Chegg. Get 1:1 help now from expert Anatomy and Physiology tutor

differences (enhanced staining) in tumour tissues.9,10 Fig. 1. - Transmission electron micrograph of normal rat tongue epithelium and lamina propria. Note basement membrane consisting of lamina lucida (small arrow) and lamina densa (large arrow). E=basal epithelial cell. [Bar=0.5 µm] Basement membrane. The BM is a unique form of the extracellular matrix (ECM) found predominantly underneath endothelial and epithelial cells. It exerts many important functions, including structural support, cell anchoring and signalling transduction.26-28 In the brain, two types of BM are found: an endothelial BM and a parenchymal BM (), which are separated by pericytes.29-31 Under. เซลล์กล้ามเนื้อและ nerve-supporting cells มี extracellular electron-dense material ล้อมรอบ เหมือนกับ basal lamina ของเนื้อผิว และให้ผลบวกกับ PAS reaction แต่เรียกว่า external lamina แทนชื่อ basement membrane ดังนั้น basal. A layer of connective tissue called the lamina propria, attaches to the basal surface of the basement membrane. Lamina propria holds the epithelial tissue glued to the deep tissues and contains blood vessels that supply the epithelial tissue. Tissue. Let's round this all up to understand how epithelial cells make the epithelial tissue

The difference between a basal lamina and a basement

The basement membrane zone (BMZ) in the skin is a critical interface between the epidermis and dermis and is a highly specialized structure that allows for communication between different cell types.1 Basement membranes throughout the body provide tissue-specific functions; however, all share similar attributes. Regardless of site, the BMZ functions as a vehicle for cellular attachment of. 'The cells of stratum basale constitute a single layer of columnar or cuboidal cells in contact with the basement membrane and connective tissue of the dermis.' 'As a basement membrane separates an epithelium from the underlying lamina propria or supportive tissue, so it also separates the follicle from the theca. The basal lamina is a layer of extracellular matrix secreted by the epithelial cells, on which the epithelium sits. New!!: Basement membrane and Basal lamina · See more » Capillary. A capillary is a small blood vessel from 5 to 10 micrometres (µm) in diameter, and having a wall one endothelial cell thick. New!!

What is the difference between basal lamina and the

Basal Lamina Connective Tissue Cell Type Versus Collagen Malignant Invasion Basement Membrane Collagen These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves The layer of fibrillar extracellular matrix immediately below the basal lamina of epithelial cells. The reticular lamina contains collagen and elastin and is secreted by connective tissue fibroblasts. The reticular lamina and the basal lamina together constitute the so-called 'basement membrane' (a term better avoided) basal cell plasma membrane and basal lamina [11 ]. Numerous studies have been done to identify the ultrastructural equivalent of the light micro­ scopic, PAS-positive basement membrane of human skin. Using a modification of the PAS staining technique on human scalp (and monkey gingiva), Swift and Saxton demonstrated that th

base·ment membrane .bā smənt n 1) a thin extracellular supporting layer that separates a layer of epithelial cells from the underlying lamina propria and is composed of the basal lamina and reticular lamina 2) basal lamina * * * the thin delicat The basal lamina and reticular lamina form the basement membranewhich helps hold it all together. Epithelial tissues are nearly completely avascular. For instance, no blood vessels cross the basement membrane to enter the tissue, and nutrients must come by diffusion or absorption from underlying tissues or the surface Progress has been made in identifying and characterizing basement membrane macromolecules, including type IV collagen, laminin, a heparan sulfate proteoglycan and bullous pemphigoid antigen. Basement membrane contains a unique collagen, type IV collagen, which is formed of pro alpha 1(IV) (Mr = 185,000) and pro alpha 2(IV) (Mr = 170,000) chains Laminins are important for Schwann cell basement membrane assembly and axonal function. In this study, we found that exogenous laminin-1, like neuromuscular laminins-2/4, formed two distinct extracellular matrices on Schwann cell surfaces, each facilitated by laminin polymerization. Assembly of one, a densely-distributed reticular matrix, was accompanied by a redistribution of cell-surface. Multitasking Basal Cells Combining Stem Cell And Innate Immune erj Simple Columnar Epithelium Basement Membrane Respiratory Epithelium Wikipedia en.wikipedia.org. 4 2 Difference Between Ciliated Epithelial Cell And Squamous pediaa.com

Previously, depending mainly on LM studies, the basement membrane was considered to be composed of two layers: (1) basal lamina, an apparently structureless layer directly beneath the basal plasmalemma of the epithelial cells, and (2) reticularlamina, the thicker layer, rich in reticular fibres, merging into the underlying connective tissue - basement membrane acetylcholinesterase neuromuscularjunction synaptic cleft Alayer of basal lamina (BL)' ensheathes each skeletal muscle fiber, and passes between nerve ' Asdefined by Sanes et al. (44), the term basal lamina (BL) refers to the 10-to 15-nm thick, electron-dense layerthat ensheatheseach skeletal muscle fiber, and th ened basal lamina, desmoplastic basal cell carcinomas showed large defects and absences in basal lamina and basement membrane immunoreactivity. Intense tumor cytoplasmic immunoreactivity for type IV collagenase was present in 13 of 15 cases of desmoplastic basal cell but absent in th The basement membrane (basal lamina) in the primary grooves was relatively smooth but did exhibit a flattened, reticulated pattern at high magnifications. SEM that illustrates the location-dependent differences in surface texture of the basement membrane. In primary dermal grooves the basement membrane has a reticulated appearance.

Difference between basal membrane and basal lamina

  1. Reticular basement membrane (RBM) thickening in asthma is considered to be the result of subepithelial fibrosis. Thus, the RBM in asthma should contain an excess of fibrils identified as interstitial collagen and the ratio of fibril to matrix should be increased above normal levels. Electron micrographs of the RBM were compared with those of interstitial collagen deeper in the bronchial wall.
  2. in (Fig.2a-d) and collagen IV (data not shown) demonstrated that the pial basement membrane was present both in mutant and in control cortices.Whereas the pial basement membrane in wild-type embryos was continuous and associated with a uniform and continuous meningeal layer (Fig. 2b,d), it was discontinuous and associated with an irregular menigeal.
  3. Illustration depicting basement membrane in relation to epithelium and endothelium. Also seen are other extracellular matrix components Latin memb
  4. Differences in the width of the intercellular spaces in the epithelial basal infolding and the renal glomerular filtration site between freeze-substitution and conventional fixation - Volume 194 Issue 2 - HIROO IWASA, HISATAKE KOND

Basal Lamina - University of Leed

  1. The Basement Membrane Interface Between the Epithelium and the Dermis: Structural Features Robin A. J. Eady, MB, FRCP \s=b\Epidermolysis bullosa is a disease originating at or close to the epidermal-dermal junction. The structural features of this interface are reviewed in detail, with particular emphasis on the basement membrane and associated intracellular and extracellular component
  2. a. basement membrane. n
  3. Human Reproduction Update 1998, Vol. 4, No. 5 pp. 486-495. European Society of Human Reproduction and Embryology. ?. Changes in basement membrane thickness in the human endometrium during the luteal phase of the menstrual cycle. Slideshow 10214539 by brotherto
  4. Basement Base ment (b[=a]sment), n. [F. soubassement. Of uncertain origin. Cf. {Base}, a., {Bastion}.] (Arch.) The outer wall of the ground story of a building, or of a part of that story, when treated as a distinct substructure. (See {Base},
  5. a) was first described in muscle as a membranaceous sheath of the most exquisite delicacy (Bowman 1840).Microscopists subsequently identified basement membranes in nearly all tissues. In the late 1970s, the discovery of the basement membrane-rich EHS tumor led to the isolation of abundant quantities of la
  6. a Of Skeletal Muscle came from here. You will be surprised to find out how convenient this device can be, and you will feel good realizing that this The Basement Membrane Basal La
  7. a. basal la
Histology at Western University of Health Sciences - StudyBlue

What are the two layers of the basement membrane, and what

Abstract Electron microscopic immunostaining was used to examine the localization of type IV collagen, laminin, entactin, heparan sulfate proteoglycan, and fibronectin within the basement membranes.. 'These connections occur through apertures in the basal laminae of both endothelial and epithelial cells.' 'On the inner surface of the cell layer, a basal lamina (an organized layer of extracellular matrix) is laid down.' 'Endothelial cells comprise the intimal layer and are supported by a thin membrane and an elastic lamina.'

Basal Lamina - an overview ScienceDirect Topic

In the subbasement-membrane fibrous elements or reticular lamina, immunostaining was confined to occasional bridges extending from the epithelial basal-lamina to that of adjacent capillaries. The joint presence of type IV collagen, laminin, heparan sulfate proteoglycan, and fibronectin in the basal lamina indicates that these substances do not occur in separate layers but are integrated into. The number of basal cells expressed per millimeter of basement membrane was strongly correlated with the height of the respiratory epithelium (r = 0.83). This anatomic relationship corresponds to the findings of Evans and associates ( 26 ), who studied the airway epithelium in several species Basement Membrane Nuclear Lamina Schwann Cells Epithelium Extracellular Matrix Neuromuscular Junction Axons Endothelium Chick Embryo Capillaries Satellite Cells, Skeletal Muscle Cells, Cultured Muscles Desmosomes Myelin Sheath Connective Tissue Salivary Ducts Epithelial Cells Pituitary Gland, Intermediate Intestinal Mucosa Sciatic Nerve.

Animal tissues and their Functions pdf |EntranceiVessels - Biology Histology with Dr at University of
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